Icp Again and Again and Again
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Around 20% of women itch in pregnancy, and but a small-scale number of these will take intrahepatic cholestasis of pregnancy (ICP). But it is important to let your health professionals know that you are itching so that they tin can perform the correct tests to see if you lot have the condition.
If you are being tested for the condition or accept been diagnosed with ICP nosotros know how lamentable this can exist. This page gives you lot some basic facts most the status equally well as signposting you to more detailed data and forms of support.
The positive news is that recent research suggests that xc% of women who have ICP tin can be reassured that their babies are free from the adventure of stillbirth due to the condition. With careful direction the ten% of babies who are at risk considering of ICP tin be born safely.
Whether you have mild or severe ICP, we are here to support y'all and provide y'all with the about up-to-engagement information in the world on this very complex condition.
For support, and to meet other women who have ICP, please join one of our Facebook groups.
What is ICP?
ICP (intrahepatic cholestasis of pregnancy, too known as obstetric cholestasis) is the most common liver status specific to pregnancy. ICP affects around five,500 women in the Britain each yr and is caused by a combination of:
- Genetics – it has been found to run in some families. Genetic changes associated with ICP occur in approximately 25% of all women and this remains an expanse of active research
- Hormones – women expecting more one baby or who have had fertility treatment appear to take a college run a risk of developing ICP
- Environs – more than cases are reported in the winter, and diet may affect the condition, but this has non then far been proven
The main symptom is itching, usually on the hands and feet, but information technology can be anywhere on the body. It may be mild or severe, and most women with ICP say that information technology's worse at nighttime.
Diagnosis, treatment and management
Your doctors volition want to brand sure that nothing else is causing the crawling, so your blood needs to be tested for other conditions every bit well as ICP. The about of import claret examination to diagnose ICP is a bile acrid exam. If the bile acid test is normal but you continue to crawling, you lot must be tested again, because research shows that you lot tin can crawling for many weeks earlier your bile acids become aberrant.
Treatment and management of ICP includes the employ of medicines, regular claret tests and possibly an early birth for the babe, depending on bile acid levels (anywhere from 35–39 weeks of pregnancy).
If you have had ICP in one pregnancy you have over an 80% gamble of developing it in a future pregnancy.
Why is ICP a problem?
ICP is known to be associated with an increased chance of:
- Infant passing meconium (poo) before nascence
- Spontaneous premature birth
- Admission to a neonatal unit
- Stillbirth (this pocket-sized risk applies to the x% of women who take astringent ICP)
The verbal cause of stillbirth in ICP has not been fully proven, but the latest research suggests that very high bile acrid levels (over 100 micromoles per litre, which you lot will normally encounter written as µmol/L) may cause the rhythm of the baby'due south center to change (known as middle arrhythmia) and make information technology end working. This theory is all the same beingness researched, and until more is known most experts recommend regular bile acid testing and an earlier nascence for those babies whose mums have bile acids over 100 µmol/L.
Information technology's of import to ask your hospital to give yous your bile acrid results within 24 hours, as they can rise of a sudden (they tin can autumn as quickly). Bile acids above 100 µmol/L may hateful that yous will need to have your baby before 39 weeks.
If your bile acid levels accept ever been below 100 µmol/L, simply your itching is and then astringent that yous cannot face waiting until 39 weeks to meet your babe, talk to your doctors nearly the possibility of an earlier nativity. Your baby volition exist considered to have reached term from 37 weeks onward, and while some babies have needed additional intendance when born at this phase in pregnancy, most volition not need any extra help.
Afterwards the birth
Once you have had your infant in that location are a few things you need to know.
It is of import that you lot have your blood checked over again after having your baby. Unremarkably in ICP your liver claret tests and bile acid tests will return to normal by effectually 6–12 weeks following the birth of your babe. However, for some women the results of these tests may continue to exist aberrant. It's important to know if they are, so that doctors tin either continue to monitor your bloods or refer yous to a liver specialist if necessary.
The only methods of contraception that are probable to crusade problems for women who have had ICP are those containing hormones. All the same, there have been no large studies regarding the use of contraception following an ICP pregnancy, so it may be possible to take the oral contraceptive pill. Speak to your doctor nearly this.
You will take a higher chance of developing liver disease, including gallstones (and some women develop these even earlier an ICP pregnancy), so it'south a good idea to have a liver blood exam in one case a year.
Enquiry has shown that girls built-in to women who have had ICP likewise have a greater gamble of developing the condition in their pregnancies. It has likewise shown that boys also equally girls can pass the genetic changes linked to the condition down through their families.
There is further prove to show that children (and their mothers) may be more affected by metabolic disease such as Blazon two diabetes in later life, just this needs more enquiry.
All photographs on this page © ICP Support 2019.
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Source: https://www.icpsupport.org/abouticp.shtml
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